B-ENT

Wegener’s granulomatosis of the temporal bone and skull base that mimicked an inflammatory myofibroblastic tumour: a case report

1.

Department of Otorhinolaryngology

2.

Department of Radiology

3.

Department of Histopathology, CHU Hautepierre, Strasbourg, France

B-ENT 2010; 6: 135-138
Read: 967 Downloads: 654 Published: 17 February 2020

Wegener’s granulomatosis of the temporal bone and skull base that mimicked an inflammatory myofibroblastic tumour: a case report. Objective: To compare two potential diagnoses of a temporal bone pseudotumour: an inflammatory myofibroblastic tumour and Wegener’s granulomatosis.

Methodology: A case of Wegener’s granulomatosis that mimicked an inflammatory myofibroblastic tumour is reported. The clinical presentation, staging of the disease, histology, and follow-up are analysed.

Results: Histopathology of the temporal bone failed to provide an accurate diagnosis, even after immunocytochemical analyses. The diagnosis of Wegener’s granulomatosis was suspected after biopsy of a pulmonary mass and was confirmed by the presence of anti-neutrophil cytoplasmic antibodies in blood samples.

Conclusion: Irrespective of the aetiology, a pseudotumour of the temporal bone should always be investigated by biology and radiology. Radiological investigations will allow staging of the disease and specific localisation for biopsies.

Files
EISSN 2684-4907