B-ENT

Vagus nerve stimulation therapy induces laryngopharyngeal reflux: a preliminary evaluation

1.

Otolaryngology Unit, San Paolo Hospital, Department of Health Sciences, Università degli Studi di Milano, Via Antonio di Rudinì, 20142 Milan, Italy

2.

Regional Centre for Epilepsy, San Paolo Hospital, Department of Health Sciences, Università degli Studi di Milano, Via Antonio di Rudinì, 20142 Milan, Italy

B-ENT 2017; 13: 275-279
Read: 923 Downloads: 524 Published: 01 February 2020

Vagus nerve stimulation therapy induces laryngopharyngeal reflux: a preliminary evaluation. Objective: Vagus Nerve Stimulation (VNS) is an approved therapy for drug- and surgery-resistant epilepsy. Despite the vagal role in regulating gastric secretion, there are no reports focusing on the prevalence of laryngopharyngeal reflux (LPR) in the VNS-implanted population. Our study aims to evaluate the prevalence of the disease in VNS-implanted patients.

Methods: All patients underwent endoscopic Otolaryngological reflux assessment based on the reflux finding score (RFS) and contextual self-assessment of symptoms by means of reflux symptom index (RSI) questionnaire.

Results: While only 3 out of 16 patients experienced symptomatic LPR (RSI>13), endoscopy documented LPR (RFS>7) in 12 out of 16 patients, there was no correlation between RSI and RFS (p.617). There has been an important trend between LPR findings since implantation was observed (p. 103).

Conclusions: LPR has a significant prevalence in VNS-implanted patients. A routine Otolaryngological follow-up could allow the prompt diagnosis and treatment of LPR in this population.

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EISSN 2684-4907