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Myxofibrosarcoma is a malignant tumor originating from fibroblast or myofibroblast, with an incidence of about 5% in soft tissue sarcomas. However, myxofibrosarcomas that originate from and are restricted to the nasal vestibule are rarely seen in the clinic. These myxofibrosarcomas are susceptible to being misdiagnosed with nasal vestibular cysts due to similar physical characteristics, such as clinical symptoms and imaging findings. In this article, we report the radiological and histopathological findings of a nasal vestibular myxofibrosarcoma and discuss the different characteristics compared with a nasal vestibular cyst. Fascial tail signs in magnetic resonance imaging, abundant myxoid matrix, and pseudolipoblastic cells in pathological findings are critical standards to make a differential diagnosis of a nasal vestibular cyst.
Cite this article as: Chen X, Zhang Z. Myxofibrosarcoma of the nasal vestibule: A case report and literature review. B-ENT. 2024 [Epub Ahead of Print]