B-ENT

Metastasis of a small cell carcinoma from undetected origin to the pituitary gland – The otolaryngologist’s view

1.

Department of Otorhinolaryngology, Head & Neck Surgery

2.

Department of Otorhinolaryngology, Head and Neck Surgery

3.

Department of Endocrinology

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Department of Histopathology, University Hospital Saint Luc, Bruxelles, Belgium

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Department of Neurosurgery, University Hospital of Mont-Godinne, Université Catholique de Louvain, Yvoir

6.

Department of Otorhinolaryngology and Head and Neck Surgery

B-ENT 2005; 1: 159-163
Read: 701 Downloads: 575 Published: 22 February 2020

Metastasis of a small cell carcinoma from undetected origin to the pituitary gland – The otolaryngologist’s view. Tumour metastasis to the anterior pituitary-hypothalamic area is rare. We present a patient who had severe headache, bitemporal quadrant hemianopsia and an expanding mass in the sella turcica as revealed by MRI. Partial resection via a transsphenoidal approach was performed and postoperative radiation therapy was initiated. Immunohistochemical investigation identified the tumour as a metastatic small cell carcinoma whose primary site remained undetected for more than 12 months despite repeated oncological evaluations. We reviewed the literature on metastatic disease of the pituitary gland.

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EISSN 2684-4907