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Isolated laryngeal tuberculosis in an immunocompetent Caucasian patient:a case report. Objective: This article reports a case of acute laryngitis with extremely rare aetiology.
Case report: An 81-year-old Caucasian man presented with dysphonia and dysphagia. Flexible nasolaryngoscopy revealed laryngeal inflammation and purulent secretions into the larynx. Treatments for mycotic, bacterial, and herpetic laryngitis were initiated successively. After the treatments failed, we proceeded with direct laryngoscopy and biopsies. The epiglottis was oedematous and irregular. Histopathological analysis of the biopsies revealed non-caseating necrotic granulomatous inflammation with giant cells. The polymerase chain reaction for Mycobacterium tuberculosis was positive. Thus, we diagnosed the patient with laryngeal tuberculosis and treated him with four antituberculosis drugs. His treatment tolerance was excellent and improvement observed regarding both clinical and endoscopic signs.
Conclusions: This case highlights that isolated laryngeal tuberculosis is rare but must be considered in the differential diagnosis of non-specific laryngeal disease.